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Dr José Antonio Fuentes García
 
 
jaf14@st-andrews.ac.uk
 

 

BACKGROUND

I obtained a BSc degree in Chemistry from the University of Valladolid ( Spain ) in 1998 and I subsequently stayed at Valladolid to work in a one year research project with Dr Alicia Maestro in the area of enzymatic resolution of racemic alcohols. After obtaining a MSc degree in Organic Chemistry, I moved to London and began my PhD research with Prof. Michael North at King's College London, in the area of catalytic asymmetric synthesis of a,a-disubstituted amino acids. On September 2004, I joined Dr Matt Clarke group and started working as a postdoctoral research assistant.

 

RESEARCH INTERESTS

Design and synthesis of new chiral ligands and their application in asymmetric catalysis.

Current research project: Using hydrogen bonds to create new asymmetric catalysts.

 

PUBLICATIONS

 

1.

 

“Synthesis of optically active b´-hydroxy-b-enaminoketones via enzymatic resolution of carbinols derived from 3,5-disustituted isoxazoles”. Fuentes, J. A.; Maestro, A.; Testera, A. M.; Bañez, J. M. Tetrahedron: Asymmetry  2000, 11, 2565-2577.

 

2

 

“The influence of imine structure, catalyst structure and reaction conditions on the enantioselectivity of the alkylation of alanine methyl ester imines catalyzed by Cu(ch-salen)”. Belokon, Y. N.; Davies, R. G.; Fuentes, J. A.; North, M.; Parsons, T. Tetrahedron Letters 2001, 42, 8093–8096

 

3.

 

"Influence of the metal and chiral diamine on metal(II)salen catalysed, asymmetric synthesis of α -methyl α -amino acids”. Belokon, Y. N; Fuentes, J. A.; North, M.; Steed, J. W. Tetrahedron  2004, 60, 3191–3204.
 

4.

 

“Influence of aromatic substituents on metal(II)salen catalysed, asymmetric synthesis of α -methyl α -amino acids”. Achard, T.; Belokon, Y. N.; Fuentes, J. A.; North, M.; Parsons, T. Tetrahedron 2004, 60, 5919–5930.

 

5.

 

Contributor to: Catalysts for Fine Chemical Synthesis, Volume 3, Metal Catalysed Carbon-Carbon Bond-Forming Reactions. Section 2. 2.2. Catalytic, Asymmetric Synthesis of α,α-Disubstituted Amino Acids Using a Chiral Copper-Salen Complex as a Phase Transfer Catalyst. Edited by S. M. Roberts, J. Xiao, J. Whittall and T. Pickett. John Wiley & Sons, 2004, ISBN: 0-470-86199-1.

 

6

 

“Self-assembly of organocatalysts: fine-tuning organocatalytic reactions”. Clarke, M. L.; Fuentes, J. A. Angew. Chem. Int. Ed. 2007, 46, 930–933.

 

7.

 

“A convenient catalyst system for microwave accelerated cross-coupling of a range of boronic acids with aryl chlorides”. Clarke, M. L.; France, M. B.; Fuentes, J. A.; Milton, E. J.; Roff, J. R. Beilstein J. Org. Chem. 2007, 3:18.

 

8.

 

“A supramolecular approach to modifying chiral ligands: co-ordination chemistry of a multifunctionalised tridentate amine-phosphine ligand”. Fuentes, J. A.; Clarke, M. L.; Slawin, A. M. Z. New Journal of Chemistry. 2008, 32, 689-693.

 

9.

 

“Deoxygenation of pyridine-N-oxides by palladium catalysed transfer oxidation of trialkylamines”. Fuentes, J. A.; Clarke, M. L. Synlett. 2008, 17, 2579-2582.

 

10.

 

“Iridium complexes of chiral diamines containing carbon and nitrogen stereocentres: Synthesis, structure and evaluation as transfer hydrogenation catalysts”. France, M. B.; Fuentes, J. A.; Slawin, A. M. Z.; Clarke, M. L. New. J. Chem. 2009, 33, 466-470.

 

11.

 

“Palladium catalysed ether synthesis using alkoxy silanes as nucleophiles.” Milton, E. J.; Fuentes, J. A.; Clarke, M. L. Org. & Bio. Chem, 2009, 7(12), 2645